Endocrine Abstracts

We describe a 91 year old woman who presented to hospital with transient loss of consciousness resulting in facial trauma. In the preceding 6 weeks she described 2 similar episodes of loss of consciousness and general malaise. She had a past medical history of pulmonary hypertension secondary to recurrent pulmonary emboli. Relevant medication included furosemide 20 mg od and life-long warfarin.On examination she had significant orbitofrontal bruising and...

Introduction: In 2017 the Roche cortisol assay underwent a generation update. The increased specificity of this assay was expected to lower cortisol results by approximately 30%. Based on a local consensus, the 30 min short Synacthen Test (SST) cortisol was lowered from 550 to 420 nmol/l. With the previous assay, a morning cortisol of ≥375 nmol/L gave a 99% PPV of an SST ‘pass’.Aims: • To compare the numbers of SSTs and the SST pass ...